ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

Alcohol dehydrogenase E chain

Intramolecular
Cysteine 98 and cysteine 112
A redox-regulated disulphide may form within Alcohol dehydrogenase E chain between cysteines 98 and 112 (97 and 111 respectively in this structure).

Details

Redox score ?
86
PDB code
6adh
Structure name
structure of triclinic ternary complex of horse liver alcohol dehydrogenase at 2
Structure deposition date
1984-01-16
Thiol separation (Å)
3
Half-sphere exposure sum ?
68
Minimum pKa ?
5
% buried
46
Peptide accession
P00327
Residue number A
98
Residue number B
112
Peptide name
Alcohol dehydrogenase E chain

Ligandability

Cysteine 98 of Alcohol dehydrogenase E chain

Cysteine 112 of Alcohol dehydrogenase E chain

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